Polynucleotides Masterclass

Advanced skin rejuvenation

Comprehensive training in Nucleofill and Ameela® polynucleotides

Comprehensive course

Learn to treat and rejuvenate your patients’ eyes, face, neck and hair

1:1 training

Intensive practical application with live models under expert supervision

Single certificate

1 certificate + 4 hours of CPD

Unlimited trainer support

Ongoing guidance to integrate treatments into your practice

Course Overview

Advanced Polynucleotide Training for Established Practitioners

The Polynucleotides Masterclass is designed for practitioners who’ve already completed foundational aesthetic training and are ready to expand their skin rejuvenation offering. This course will equip you with the knowledge and practical skills to safely and effectively integrate polynucleotide treatments into your practice.

Polynucleotides represent a fairly recent shift in skin rejuvenation. Unlike traditional approaches that merely address surface-level concerns, polynucleotides work at a cellular level to stimulate biostimulation and bio-restructuring. This means your patients will benefit from genuine tissue regeneration rather than temporary cosmetic improvement.

Whether you’re looking to offer comprehensive skin rejuvenation or enhance your existing treatment offering, this masterclass provides the clinical foundation to deliver exceptional results with confidence.

Course Curriculum

What's included

Gain a deep understanding of both Nucleofill and Ameela®, their unique formulations of polynucleotides, and how they work to restore skin firmness, elasticity, and overall health. Special focus is given to Nucleofill for practical training and applications.

You will learn how to seamlessly incorporate polynucleotide treatments into your practice. This integration is not just about the technical application of the products, but it’s about creating a holistic patient experience that considers each step of the process. From initial consultation through to post-treatment care, you will gain the skills necessary to advise patients on the best treatment options for their unique needs, and tailor treatments accordingly.

You will learn the full range of skin issues that Polynucleotides are capable of addressing. From eyebags and periocular wrinkles to skin laxity, contouring, and biostimulation.

We will cover the benefits of Nucleofill, including its action against free radicals and its ability to improve tissue regeneration and restore skin tone and elasticity.

Master the consultation process, patient assessment, and comprehensive aftercare protocols. You’ll learn how to advise patients on treatment options, tailor treatments to individual needs, and guide them through the entire patient journey.

The course will provide you with in-depth knowledge of how polynucleotide treatments can be used to enhance healing processes, improve tissue health and accelerate recovery times.

This understanding will allow you to present polynucleotides as a compelling option for patients looking for ways to speed up their recovery after surgery, as well as to maintain and enhance their results long after the surgical procedure.

Get hands-on training using:

  • Nucleofill Eyes – treating eyebags and periocular wrinkles with precision

  • Nucleofill 20 and 25 – rejuvenating mature and younger skin, improving tone, elasticity, and reducing fine lines

  • Nucleofill Hair – scalp treatments with moisturising properties

You’ll learn how these products can be used to treat various areas including the face, neck, hair, and hands, improving both superficial and deep skin concerns.

Receive personalised instruction and constructive feedback from an experienced Avanti trainer as you perform treatments under direct supervision. After the course, you’ll have free ongoing support and access to a closed Delegates groups where you can ask questions, share treatment plans and learn from your fellow delegates. 

You can also receive immediate 24-hour emergency trainer support via the Avanti app should you have any emergency issues, e.g. a patient complication.

Treatment areas

Areas You'll Treat

From conducting the initial consultation through to providing aftercare instructions, you will guide your patient through the entire process from start to finish in the following treatment areas:

The delicate eye area demands precision and understanding. You’ll learn techniques for treating eyebags, periocular wrinkles, and the subtle volume loss that contributes to an aged appearance.

This area represents both a significant patient concern and an excellent entry point into polynucleotide treatments.

Learn to distinguish between treating younger skin (Nucleofill 20) and mature skin (Nucleofill 25). You’ll understand how polynucleotides improve skin tone, reduce fine lines and wrinkles, and restore elasticity across different skin types and ages.

Hair loss and scalp ageing are increasingly common patient concerns. You’ll learn how Nucleofill Hair’s moisturising and regenerative properties address scalp health, potentially supporting hair growth and overall scalp vitality.

Beyond treating individual concerns, you’ll learn how to use polynucleotides as part of a comprehensive full-face rejuvenation strategy, addressing volume loss, restoring skin quality, and achieving natural-looking results that enhance features rather than distort facial anatomy.

The Skin Rejuvenation Bundle

Four advanced dermal filler masterclasses over an intensive weekend programme that represents significantly better value.
Meet your Lead Trainer

Dr. Rikin Parekh

Dr. Rikin Parekh (B.D.S) is a globally recognised authority in facial aesthetics, blending 19+ years of clinical expertise with a dedication to advancing medical education. Originally trained in dentistry, he entered aesthetics in 2006 and ascended to become a Senior Non-Surgical Clinician at one of the UK’s largest plastic surgery groups. Today, he serves as Medical Director of Avanti Aesthetics Academy and his Central London clinic.

As a Key Opinion Leader for leading industry brands, Dr. Parekh regularly presents at international conferences and trains medical professionals worldwide. His teaching style prioritises anatomical precision, complication management, and ethical practice.

Under Dr. Parekh’s guidance, thousands of medical professionals have transformed their careers, establishing safe, successful aesthetic practices rooted in clinical excellence.

Trusted by 5000+ delegates

What our Delegates say

Avanti is built on a foundation of peer support and expert guidance. Our delegates and trainers form a strong, supportive community where you can learn, grow, and achieve your career goals together.

Danielle W
Danielle W
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Leonie Murphy
Leonie Murphy
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 Donal Patel
Donal Patel
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Natalie Blake
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Manika R
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Thusha Sucindran
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Priya Virdi
Priya Virdi
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Bhavik Shah
Bhavik Shah
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T S
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Savan Shah
Savan Shah
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Tracey Moynihan
Tracey Moynihan
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Sahra Jabbar
Sahra Jabbar
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Simple, Transparent Pricing

You have the option to pay the full course fee at the time of booking using a credit or debit card, or choose a monthly payment plan and split your training fee over 3, 6 or 9 months.

Comprehensive

Polynucleotides Masterclass

Standalone masterclass option or enhance your skills as part of the Skin Rejuvenation Bundle.

From £93 / month inc. VAT

Better value. More comprehensive.

The Skin Rejuvenation Bundle

The Skin Rejuvenation Bundle combines four advanced dermal filler masterclasses into an intensive weekend programme. By training in multiple complementary skin rejuvenation techniques together, you'll gain a holistic understanding of how different treatments work synergistically and be able to offer comprehensive skin solutions to your patients.

From £221 / month inc. VAT
Save £585 vs separate bookings

Comprehensive

Polynucleotides Masterclass

Standalone masterclass option or enhance your skills as part of the Skin Rejuvenation Bundle.

£495 inc. VAT

Better value. More comprehensive.

The Skin Rejuvenation Bundle

The Skin Rejuvenation Bundle combines four advanced dermal filler masterclasses into an intensive weekend programme. By training in multiple complementary skin rejuvenation techniques together, you'll gain a holistic understanding of how different treatments work synergistically and be able to offer comprehensive skin solutions to your patients.

£1,895 inc. VAT
Save £585 vs separate bookings

Frequently asked questions

This comprehensive course includes theoretical training on both Nucleofill and Ameela®, followed by practical hands-on training with Nucleofill. This includes in-depth exploration of product knowledge, indications and benefits, practical applications, treatment protocols, and patient consultation and aftercare.

Yes, Avanti provides both models and products for the training. Our delegates treat their own patients from consultation to aftercare under one-to-one supervision. We also accommodate requests for bringing your own models.

While the primary focus of this course is on treating various skin concerns, the knowledge gained from understanding the properties and actions of polynucleotides can potentially be applied to hair rejuvenation treatments as well.

Both Nucleofill and Ameela® use polynucleotides, which work to restore skin firmness and elasticity and protect against cellular damage. Unlike some other treatments, they focus on biostimulation and bio-restructuring, offering a non-invasive yet highly effective approach to skin rejuvenation.

You’ll be trained by highly experienced Avanti trainers, led by Dr. Rikin Parekh, who has over 16 years of experience in the Aesthetics Industry. Our trainers are at the forefront of facial aesthetics and provide a supportive one-on-one experience during your hands-on training.

We offer free ongoing support to our polynucleotide training delegates. You will have access to our closed Delegates groups where you can ask questions and learn from colleagues. 

Our delegates can receive 24-hour emergency trainer support via the Avanti app upon completion of training in case of patient complications or other emergencies. If you have any emergency issues, e.g. a patient complication, you will be able to contact one of our experts for immediate advice if required.

The training takes place at our well-equipped venue located at 140 New Cavendish Street, London W1W 6YE, in the heart of Central London.
Avanti stands out because of its comprehensive training and free, unparalleled support to delegates not just during the course but before and after as well. We understand the challenges of applying new skills in practice and offer multiple methods for continued learning and assistance, including an Emergency Mobile Hotline for immediate advice.

More Questions?
Chat with us.

Schedule a time to chat with Julie, our Academy Manager, to learn how Avanti can help launch your aesthetics career.

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