Choosing the Right Injectable: Skin Boosters vs Nucleofill – A Comprehensive Guide

When it comes to non-surgical cosmetic treatments, choosing the right injectable is essential for achieving the best possible results. Aesthetic practitioners are faced with a multitude of options, each with its own unique set of benefits and drawbacks. In this blog post, we take a closer look at two of the most popular injectables on the market: Skinboosters and Nucleofill Polynucleotides. With in-depth information and comparisons, this comprehensive guide will help aesthetic practitioners make an informed decision when choosing the right injectable for their patients.




In the field of aesthetics, having a variety of injectable treatments at your disposal can be hugely beneficial to your patients. However, with so many options available, it can be challenging to choose which products to use and when. In this article, we will be exploring the differences between two popular injectable treatments: Skinboosters and Nucleofill Polynucleotides.

What are Skinboosters?

Skinboosters are a type of injectable treatment that aim to hydrate and rejuvenate the skin. They are made from hyaluronic acid, a naturally occurring substance in the skin, and are designed to add moisture and volume to the deeper layers of the skin. This helps to improve skin texture, reduce fine lines, and enhance skin health, resulting in a more youthful and radiant appearance. Skinboosters are often used for treating mild to moderate signs of aging, such as fine lines and wrinkles, as well as for improving skin hydration.

What are Nucleofill Polynucleotides?

Nucleofill is a type of filler that is used to add volume and treat fine lines and wrinkles. It is also made from hyaluronic acid, but its primary focus is on correcting specific problem areas, such as sunken cheeks, under-eye hollows, and thin lips. Nucleofil is applied in a more targeted manner than skinboosters, and the results are more immediate, with a fuller and more youthful appearance.

Which is Right for Your Patients?

One key difference between the two treatments is the application process. Skinboosters are typically applied to a larger area of the face, while nucleofill is more focused on specific problem areas. Additionally, the composition of the hyaluronic acid in each treatment may differ, affecting the results and duration of the treatment.

Another important factor to consider is the duration of the results. Skinboosters typically require multiple sessions for optimal results, while nucleofil results can often be achieved in one session. However, the results of skinboosters are more gradual and subtle, providing overall skin hydration, while nucleofil results are more immediate and targeted to specific areas of concern.


In conclusion, both Skinboosters and Nucleofill Polynucleotides have their place in the world of aesthetics. Both are effective cosmetic treatments that offer quick and non-invasive solutions for a variety of skin concerns.

Choosing the right one for your patient will ultimately depend on their individual needs and goals. If they are looking for overall skin hydration and rejuvenation, skinboosters may be the right choice. If they are looking to correct specific problem areas, nucleofill may be a better option. It’s important to take the time to consult with your patients and thoroughly assess their skin condition before making a recommendation.

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